The therapeutic promise of small-RNA therapeutics is limited, not only by the lack of delivery vehicles, but also by the inability of the small RNAs to reach intracellular compartments where they can Multi-pin be biologically active.We previously reported successful delivery of functionally active miRNAs via receptor-mediated endocytosis.This type
ABSTRACT Objectives: the purpose of this study was to evaluate the outcome of rectal cancer surgery, in a unit adopting the principles of total mesorectal excision (TME) with a high restorative procedure rate and with a low rate of abdominoperineal excision (APE).Methods: we enrolles patients with extraperitoneal rectal cancer undergoing TME or TME
3D Concrete Printing (3DCP) has been gaining popularity in the past few years.Due to the nature of line-by-line printing and the slump of the material deposition in each extruded line, 3D printed structures exhibit obvious lines or marks at the layer interface, which affects surface finish quality and potentially affect bonding strength between lay
Recent research has focused on the monitoring of global-scale online data for improved detection of epidemics, mood patterns, movements in the stock market political revolutions, box-office revenues, consumer behaviour and many other important phenomena.However, privacy considerations and the sheer scale of data available online are quickly making
Abstract Prospective memory, the ability to remember to execute an intended action at the appropriate moment in the future, is frequently assessed with standardized questionnaires.Prospective-memory abilities strongly depend on the different strategies people use to remember their intentions.In this study, we introduce the short version of the Meta